近期研究成果

106年04-06月研究成果

1. Li CY, Lo IW, Wang SW, Hwang TL, Chung YM, Cheng YB, Tseng SP, Liu YH, Hsu YM, Chen SR, Hu HC, Chang FR*, Wu YC*. “Novel 11-norbetaenone isolated from an entomopathogenic fungus Lecanicillium antillanum”, Bioorganic &. Bioorg Med Chem Lett. 2017 May 1;27(9):1978-1982.

2. Hsieh MT, Chang LC, Hung HY, Lin HY, Shih MH, Tsai CH, Kuo SC, Lee KH. New bis(hydroxymethyl) alkanoate curcuminoid derivatives exhibit activity against triple-negative breast cancer in vitro and in vivo. Eur J Med Chem. 2017 May 5;131:141-151.

3. Yen HR*, Lai WY, Muo CH, Sun MF. Characteristics of Traditional Chinese Medicine Usage in Pediatric Cancer Patients: A Nationwide, Retrospective, Taiwanese-registry, Population-based Study. Integrative Cancer Therapies. 2017 Jun;16(2):147-155.

4. Fleischer T, Chang TT, Chiang JH, Sun MF, Yen HR*. Improved Survival With Integration of Chinese Herbal Medicine Therapy in Patients With Acute Myeloid Leukemia: A Nationwide Population-Based Cohort Study. Integrative Cancer Therapies. 2017 Jun;16(2):156-164.

5. Kuo YT, Chang TT, Muo CH, Wu MY, Sun MF, Yeh CC, Yen HR*. Use of Complementary Traditional Chinese Medicines by Adult Cancer Patients in Taiwan: A Nationwide Population-based Study. Integrative Cancer Therapies. 2017 Jun1:1534735417716302.doi:10.1177/1534735417716302. [Epub ahead of print]

6. Chang CT, Korivi M, Huang HC, Thiyagarajan V, Lin KT, Huang PJ, Liu JY, Hseu YC, Yang HL. Inhibition of ROS production, autophagy or apoptosis signaling reversed the anticancer properties of Antrodia salmonea in triple-negative breast cancer (MDA-MB-231) cells. Food Chem Toxicol. 2017 May; 103:1-17.

7. Tsai YF, Chu TC, Chang WY, Wu YC, Chang FR, Yang SC, Wu TY, Hsu YM, Chen CY, Chang SH, Hwang TL. 6-Hydroxy-5,7-dimethoxy-flavone suppresses the neutrophil respiratory burst via selective PDE4 inhibition to ameliorate acute lung injury. Free Radic Biol Med. 2017 May, 106:379-392.

8. Chang YY, Liu YC, Kuo YH, Lin YL, Wu YS, Chen JW, Chen YC*. Effects of antrosterol from Antrodia camphorata submerged whole broth on lipid homeostasis, antioxidation, alcohol clearance, and antiinflammation in livers of chronic-alcohol fed mice. J. Ethnopharmaco. 2017 Apr 18, 202, 200-207.

9. Wu KC, Huang SS, Kuo YH*, Ho YL, Yang CS, Chang YS, Huang GJ. Ugonin M, a Helminthostachys zeylanica Constituent, Prevents LPS-Induced Acute Lung Injury through TLR4-Mediated MAPK and NF-κB Signaling Pathways. Molecules. 2017 Apr 1, 22 , 573.

10. Tsai TH, Yu CH, Chang YP, Lin YT, Huang CJ, Kuo YH*, P. J. Tsai. Protective Effect of Caffeic Acid Derivatives on tert-Butyl Hydroperoxide-Induced Oxidative Hepato-Toxicity and Mitochondrial Dysfunction in HepG2 Cells. Molecules. 2017 Apr 28, 22, 702.

11. Yang CS, Chen JJ, Huang HC, Huang GJ, Wang SY, Sung PJ, Cheng MJ, Wu MD, Kuo YH*. New Benzenoid Derivatives and Other Constituents from Lawsonia inermis with Inhibitory Activity against NO Production. Molecules. 2017 Jun 5, 22(6), 936.

12. Hsiao G, Chi WC, Pang KL, Chen JJ, Kuo YH , Wang YK, Cha HJ, Chou SC, Lee TH. Hirsutane-Type Sesquiterpenes with Inhibitory Activity of Microglial Nitric Oxide Production from the Red Alga-Derived Fungus Chondrostereum sp. NTOU4196. J. Nat. Prod. 2017 May 26, 80(5) ,1615-1622.

13. Lin YC, Chang TT, Chen HJ, Wang CH, Sun MF, Yen HR*. Characteristics of Traditional Chinese Medicine Usage in Children with Precocious Puberty: A Nationwide Population-Based Study. Journal of Ethnopharmacology. 2017 Jun 9; 2015: 231–239.

14. Lu CY, Chang YC, Hua CH, Chuang C, Huang SH, Kung SH, Hour MJ, Lin CW*. Tubacin, an HDAC6 Selective Inhibitor, Reduces the Replication of the Japanese Encephalitis Virus via the Decrease of Viral RNA Synthesis. Int J Mol Sci. 2017 May 1;18 (5).

15. Wang CY, Lu CY, Li SW, Lai CC, Hua CH, Huang SH, Lin YJ, Hour MJ, Lin CW*. SARS coronavirus papain-like protease up-regulates the collagen expression through non-Samd TGF-β1 signaling. Virus Res. 2017 Apr 13;235:58-66.

16.Lin TH, Yen HR, Chiang JH, Sun MF, Chang HH, Huang ST. The use of Chinese herbal medicine as an adjuvant therapy to reduce incidence of chronic hepatitis in colon cancer patients: A Taiwanese population-based cohort study. J Ethnopharmacol. 2017 Apr 18;202:225-233.

17. Pang JS, Yen JH, Wu HT, Huang ST. Gallic Acid Inhibited Matrix Invasion and AP-1/ETS-1-Mediated MMP-1 Transcription in Human Nasopharyngeal Carcinoma Cells. Int J Mol Sci. 2017 Jun 24;18(7). pii: E1354. doi: 10.3390/ijms18071354.

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