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Ongoing Projects

2017 Projects Categorization and Research Focus

NO. Research topic PI
chm106-1 First class of GSTO inhibitor as adjuvant therapy to boost efficacy of platinum-based chemotherapy
Yang-Chang Wu / Chuan-Chen Yang
chm106-2 Development of New Curcuminoids as Anticancer Drug Candidates
Sheng-Chu Kuo
chm106-3 Develop ADAM9 inhibitors and CDCP1 cleavage blockade to reduce lung cancer and breast cancer metastases
Yuh-Pyng Sher
chm106-4 Hedyotis diffusa Willd for Modulation of Immunity in Anti-tumor Responses
Hung-Rong Yen / Song-Ying Chyi / Hui-Chi Huang
chm106-5-1 New Drugs Development of Antrodia cinnamomea

Yang-Chang Wu / Tung-Ying Wu / Chih-Hsin Tang
chm106-5-2 Yueh-Hsiung Kuo
chm106-5-3 You-Cheng Hseu
chm106-6-1 New drug development from Indigo Naturalis for targeting IL-17A in autoimmunity
Chia-Lin Lee/Hung-Rong Yen
chm106-6-2 New drug development from Indigo Naturalis for targeting IL-17A in infectious disease
Cheng- Wen Lin
chm106-7 The clinical trial of PHY606 in the patients with iron deficiency anemia
Sheng-Teng Huang
chm106-8 The clinical trial of BYHWT in the patients with diabetic nephropathy
Sheng-Teng Huang
chm106-9 The protective effects of Cordyceps compositions in LPS-induced acute lung injury in mice and its anti-inflammatory molecular mechanism Wen-Tsong Hsieh/Yueh-Hsiung Kuo
chm106-10 Growth suppression of Ganoderma tsugae against prostate cancer cells Ming-Ching Kao/Shen-Chieh Chou

 

2016 Projects Categorization and Research Focus

NO. Research topic PI
1-1 Development of Taiwanese Fern Derived Compounds as GSTO Inhibitor for Cancer                                                 Yang-Chang Wu
1-2 Development of Camptothecin Derivatives as New Anticancer Drugs                    Sheng-Chu Kuo
1-3 Targeted New Drug Development for GBM – 2nd Generation Drug of Interstitial Chemotherapy Shinn-Zong Lin/Horng-Jyh Harn
1-9 Development of ADAM9 inhibitors to block lung cancer metastases                      Yuh-Pyng Sher
2-1 New Drugs Development of Antrodia cinnamomea Yang-Chang Wu /Chih-Hsin Tang /Yueh-Hsiung Kuo
2-4 Preclinical Study of Novel Diabetic Peptide Drugs Derived from Tian-Hwa-Fen                                Tin-Yun Ho
2-6 New Drug Development of Indigo Naturalis Ointment                                      Hung-Rong Yen/Chia-Lin Lee

 

2015 Projects Categorization and Research Focus

NO. Research topic Leader PI
Main projects : Cancer
1-1 Research & Development of New Anti-cancer Drug WYC-0209-241. Yang-Chang Wu Yang-Chang Wu
1-2 Synthesis and biological evaluation of new fluorinated betulinic acid derivatives as antitumor agents. Sheng-Chu Kuo
1-4 Exploring the Alternative Splicing or Epigenome modulation Chinese drugs and Investigating the Mechanism. Jan-Gowth Chang
1-6 Anti-inflammation, anti-diabetes, and anti-osteoporosis from the major components of Antrodia compharata, and synthesis of cytotoxic lignan compounds with skeletons of 2-phenyldihydrobenzofuran and 2-phenylbenzofuron. Yueh-Hsiung Kuo
1-9 Development of ADAM9 inhibitors to block lung cancer metastases. Yuh-Pyng Sher
2-1 New Drugs Development of Antrodia cinnamomea.
Using pure Chinese Medicine compound library to discover anti-bone cancer agent.
Yang-Chang Wu
Chih-Hsin Tang
G-1 Anticancer Section: Anti-leukemia animal model and anticancer mechanisms of Ganoderma tsugae ethanoal extract and its components Jing-Gung Chung
Main project : Metabolism
1-8 The New Drug development of Rice Hull Arabingolalatan in Cancer Immunotherapy. Tin-Yun Ho Wen-Chuan Lin
2-2 Novel anti-fatty liver, fibrosis and liver cancer drugs from Artemisia capillaris Thunb. Shung-Te Kao
2-4 Research and Development of Oral Diabetic Insulin-Replacement Drugs Tin-Yun Ho
2-5 Functional and Mechanistic Investigation of Immunologic Modulation on Atopic Dermatitis by Sophora flavescen Ait.    Hung-Rong Yen
Ching-Liang Hsieh
G-2 Anti-photoaging and Dermato-protective Properties of Traditional Chinese Medicine in UVA-irradiated Human Skin Cells.
Treatment MST3 transgenic mice induced renal hypertension from Chinese herbs.
Jin Bin Wu
G-1 N/A Jing-Gung Chung
Main project : Translational Medicine
1-3 Targeted New Drug Development for GBM – 2nd Generation Drug of Interstitial Chemotherapy. Horng-Jyh Harn Shinn-Zong Lin
Horng-Jyh Harn
1-7 Application of Chinese medicine-containing biomaterials on nerve regeneration. Yueh-Sheng Chen
G-3 Translational medicine, clinical research and new drug development for Tradition Chinese medicine of human disease. Shung-Te Kao