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賀 中草藥研究中心 吳東穎博士團隊發表於國際頂尖期刊

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6-Hydroxy-5,7-dimethoxy-flavone suppresses the neutrophil respiratory burst via selective PDE4 inhibition to ameliorate acute lung injury.

期刊雜誌名稱: Free Radic Biol Med. 2017, 106:379-392. (SCI) (Impact factor: 5.606; Category: Biochemistry & Molecular Biology; Ranking: 42/286, 14.68%)

簡介: Over-activated neutrophils produce enormous oxidative stress and play a key role in the development of acute and chronic inflammatory diseases. 6-Hydroxy-5,7-dimethoxy-flavone (UFM24) showed inhibitory effects on human neutrophil activation and salutary effects on lipopolysaccharide (LPS)-induced acute lung injury (ALI) in mice.

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